- sanjay@cusb.ac.in
- sanjaycdri@gmail.com
- +91- 8287333939
Specialization :
Malaria, Cardiovascular, and Blood Cancer
EXPERIENCE : Research and Teaching : > 12 years
- Malaria research at CSIR-CDRI, Lucknow , U.P, India [2003-2008].
- Cardiovascular research in ion channels, metabolic syndrome, & restenosis in USA [ 2008-2012]
- Blood cancer (Acute leukemia) research in USA [ 2012-2019].
- Teaching experience at Lalit Narayan Mithila University, Darbhanga [ 2019-2020] and at Central University of South Bihar, Gaya [ 2020 – till date].
Research Interests:
Research (in APA Style)
- Recent Publications:
- Venkateswararao. Podile. & Subramanian Shanmugam, Effect of Digital India on Political Empowerment of Rural women and Urban Women, International Journal of Psychology and Education, ISSN ; 00333077, vol 57(9), 2020, Pp565-570 (Scopus Indexed)
- Subramanian. S and Yamuna. D., Management of Non-Performing Assets with reference to Asset Quality in Public Sector Banks, Our Heritage Journal, ISSN: 0474-9030 Volume 68, Issue 1 Jan, 2020 ( UGC -CARE listed Journal)
- Yamuna. D and Subramanian. S, Bank Level Challenges on Management of Loan Quality in Public Sector Banks, International Journal of Recent Technology and Engineering (IJRTE), ISSN: 2277-3878, Volume-8 Issue-2S4, July, 2019, pp. 650-655 (Scopus Indexed)
- Venkateswararao. Podile. And Subramanian Shanmugam ., Inventory Turnover in Engineering Micro and Small Enterprises, International Journal of Solid State of Technology, Vol. 63 Issue:2S, 2020, pp. 532-537 (Scopus indexed)
- Book:
- “Quality Enhancement and Sustenance in Managerial Practices” Chennai, Ayyappan Publishing house, 2010, ISBN No: 978-81-909575-2-6.
- The significance of decision making in Global Business Scenario” Chennai, G.K Publishers, 2012, ISBN No: 978-93-81208-07-6.
Our malaria research investigates new target or active antimalarial molecules which can be used for new antimalarial drugs designing or novel candidate for vaccine development. We would also study TRPC channels role in metabolic syndrome and signaling mechanism involved in restenosis using human smooth cells /rat model. Acute promyelocytic leukemia [APL] is a blood cancer usually formed due to chromosomal mutation between chromosome 15 and 17. My research aims for identification of novel and new target in APL using APL cell lines, transgenic, and xenograft mice model through utilization of advance molecular, imaging , and RNAi techniques.
- Publications :
- Tchounwou PB, Dasari S, Noubissi F, Ray P, Kumar S ( 2021). Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy. Journal of Experimental Pharmacology, 13, 303-328, doi: 10.2147/JEP.S267383..
- Kumar S, Tchounwou PB.(2020). Trisenox disrupts MDM2-DAXX-HAUSP complex and induces apoptosis in a mice model of acute promyelocyte leukemia. Journal of Cancer 11, 4373-4383.
- Brown A, Kumar S, Tchounwou PB.(2019). Cisplatin-Based Chemotherapy of Human Cancers. Journal of Cancer Science and Therapy 11, 097-103.
- Tchounwou PB, Yedjou CG, Udensi UK, Pacurari M, Stevens JJ, Patlolla AK, Noubissi F, Kumar S. (2019). State of the science review of the health effects of inorganic arsenic: perspectives for future research. Environmental Toxicology 34, 188-202.
- Kumar S, Brown A, Tchounwou PB.(2018). Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells. Oncotarget 9 , 33138-33148.
- Kumar S, Farah IO, Tchounwou PB.(2018). Trisenox induces cytotoxicity through phosphorylation of mitogen‐activated protein kinase molecules in acute leukemia cells. Journal of Biochemical and Molecular Toxicology 32 , e22207.
- Kumar S, Tchounwou PB.(2015). Molecular mechanism of cisplatin cytotoxicity in acute leukemia cells. Oncotarget 6, 40734-40746.
- Kumar S, Yedjou CG, Tchounwou PB.(2014). Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells. Journal of Experimental and Clinical Cancer Research 33, 42.
- Kundumani-Sridharan V, Singh NK, Kumar S,.Rao GN .(2013). Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration and proliferation and injury-induced vascular wall remodeling. Journal of Biological Chemistry 288, 22150-22162.
- Singh NK, Kundumani-Sridharan V, Kumar S, Verma SK, Kotla S, Mukai H, Heckle MR, Rao GN. (2012). PKN1 is a novel substrate for NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood vessel wall remodeling Journal of Biological Chemistry. 287, 36291-36304.
- Kumar S, Chakraverty S, Balbosa C, Brustovetsky T, Brustovetsky N, Obukhov AG.(2012). Mechanisms controlling neurite outgrowth in Rat pheochromocytoma cell line: The role of TRPC channels. Journal of Cellular Physiology 227, 1408-1419.
- Chakraverty S, Berwick ZC, Bartlett PJ, Kumar S, Thomas AP, Sturek M, Tune JD, Obukhov AG.(2011). Bromoenol Lactone (BEL) inhibits Cav1.2, and TRPC channels. Journal of Pharmacology and Experimental Therapeutics.339, 329-340.
- Neeb ZP, Edwards JM, Alloosh MA, Long X, Bratz IN, Peller CR, Byrd JP, Kumar S, Obukhov AG, Sturek M.(2010). Exercise training decreases store-operated Ca2+ entry associated with metabolic syndrome and coronary atherosclerosis. Cardiovascular Research 85, 631-640.
- Hu G, Oboukhova EA, Kumar S, Sturek M, Obukhov AG.(2009). Canonical Transient Receptor Potential Channels Expression is Elevated in a Porcine Model of Metabolic Syndrome. Molecular. Endocrinology 23, 689-699.
- Kumar S, Guha M, Choubey V, Maity M, Srivastava K, Puri SK, Bandyopadhyay U. (2008). Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species. Free Radical and Biological Medicine 44, 602-613.
- Kumar S, Das SK, Dey S, Maity P, Guha M, Choubey V, Panda G, Bandyopadhyay U. (2008). Antiplasmodial Activity of [(Aryl) arylsulfanylmethyl]pyridine. Antimicrobial Agents Chemotherapy 52, 705-715.
- Kumar S, Guha M, Choubey V, Maity M, Bandyopadhyay U. (2007).“Antimalarial drugs inhibiting hemozoin (β hematin) formation: A mechanistic update. Life Sciences. 80 , 813-828.
- Kumar S, Bandyopadhyay U. (2005). “Free heme toxicity and its detoxification systems in human. Toxicology Letters. 157 , 175-188.
- Guha M, Kumar S, Choubey V, Maity M, Bandyopadhyay U.(2006). “Apoptosis in the liver during malaria: Role of oxidative stress and implication of the mitochondrial pathway.” Federation of American Society for Experimental Biology Journal 20 , E439-E449.
- Choubey V, Guha M, Maity P, Kumar S, Raghunandan R, Maulik PR, Halder UC, Bandyopadhyay U.(2006). “Molecular characterization and localization of Plasmodium falciparum choline kinase.” Biochimical Biophysics Acta 1760, 1027-1038.
- Guha M, Choubey V, Maity P, Kumar S, Shrivastava K , Puri SK, Bandyopadhyay U.(2007). Overexpression, purification and localization of apoptosis related protein from Plasmodium falciparum. Protein Expression and Purification 52 , 363-372.
- Choubey V, Maity P, Guha M, Kumar S, Shrivastava K, Puri SK, Bandyopadhyay U.(2007). Inhibition of Plasmodium falciparum choline kinase by hexadecyltrimethylammonium bromide: A possible antimalarial mechanism of hexadecyltrimethylammonium bromide. Antimicrobial. Agents Chemotherapy. 51, 696-706.
- Patent:
- Book: Tchounwou PB, Udensi KU, Isokpehi RD, Yedjou CG, Kumar S.(2015). Arsenic and cancer. Chapter 23 in Handbook of Arsenic Toxicology. Flora SJS (Ed). Elsevier Inc. London. pp 533-555.
- Awards:
- Editorial board member of GERF Bulletin of Bioscience.
- Reviewer of four international journals: - (i) Circulation, ii) Circulation Research, (iii) Life Sciences, (iv) Environmental Toxicology.
- Ramalingaswami Re-entry Fellowship [2019], Department of Biotechnology, Govt. Of India.
- Presidential Creative Award (2015) [Jackson State University, Jackson, MS, USA].
- Research Excellence Award (2014) [Research Centers in Minority Institutions (RCMI), USA].
- Junior Research Fellow[JRF] and Senior Research Fellow[SRF] (2003-2007) [Council of Scientific and Industrial Research (CSIR), India].
- Projects:
Ramalingaswami fellow [Since November 2019 ].
Established under the Central Universities Act, 2009 (Section 25 of 2009) as Central University of Bihar (CUB) and the name since changed by the Central Universities (Amendment) Act, 2014 to Central University of South Bihar (CUSB) is an institution of higher learning in the state of Bihar.
Reception : 0631 – 2229 530
Admission : 0631 – 2229 514 / 518
– 9472979367
EMAIL : info@cusb.com
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